ASCC2 抗体 (AA 488-757)
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北京 101111
Quick Overview for ASCC2 抗体 (AA 488-757) (ABIN6137169)
抗原
See all ASCC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 488-757
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序列
- LACLEYYHYD PEQVINNILE ERLAPTLSQL DRNLDREMKP DPTPLLTSRH NVFQNDEFDV FSRDSVDLSR VHKGKSTRKE ENTRSLLNDK RAVAAQRQRY EQYSVVVEEV PLQPGESLPY HSVYYEDEYD DTYDGNQVGA NDADSDDELI SRRPFTIPQV LRTKVPREGQ EEDDDDEEDD ADEEAPKPDH FVQDPAVLRE KAEARRMAFL AKKGYRHDSS TAVAGSPRGH GQSRETTQER RKKEANKATR ANHNRRTMAD RKRSKGMIPS
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 488-757 of human ASCC2 (NP_115580.2).
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亚型
- IgG
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anti-Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2) (AA 1-757) antibody
ASCC2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2) (AA 672-757) antibodyASCC2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2) antibodyKD Validated ASCC2 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB6350 unconjugated
anti-Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2) antibodyASCC2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2) (AA 672-757) antibodyASCC2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2) (AA 672-757) antibodyASCC2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2) (AA 612-661) antibodyASCC2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ASCC2 (Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2))
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别名
- ASCC2
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背景
- Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. Involved in activation of the ribosome quality control (RQC pathway, a pathway that degrades nascent peptide chains during problematic translation. As part of the ribosome quality control trigger (RQT complex, recognizes ZNF598-dependent ubiquitination of stalled ribosomes (By similarity.,ASCC2,ASC1p100,p100,Signal Transduction,ASCC2
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分子量
- 41 kDa/77 kDa/86 kDa
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基因ID
- 84164
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UniProt
- Q9H1I8
抗原
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