ARHGAP44 抗体 (AA 666-772)
Quick Overview for ARHGAP44 抗体 (AA 666-772) (ABIN6137082)
抗原
See all ARHGAP44 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 666-772
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序列
- MADQSAGQPS PVSLSPTPPS TPSPYGLSYP QGYSLASGQL SPAAAPPLAS PSVFTSTLSK SRPTPKPRQR PTLPPPQPPT VNLSASSPQS TEAPMLDGMS PGESMST
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 666-772 of human ARHGAP44 (NP_055674.4).
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亚型
- IgG
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anti-rho GTPase Activating Protein 44 (ARHGAP44) (AA 784-811), (C-Term) antibody
ARHGAP44 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB30114 unconjugated
anti-rho GTPase Activating Protein 44 (ARHGAP44) (AA 791-819), (C-Term) antibodyARHGAP44 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ARHGAP44 (rho GTPase Activating Protein 44 (ARHGAP44))
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别名
- ARHGAP44
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背景
- GTPase-activating protein (GAP that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP-bound states. Acts as a GAP at least for CDC42 and RAC1. In neurons, is involved in dendritic spine formation and synaptic plasticity in a specific RAC1-GAP activity (By similarity. Limits the initiation of exploratory dendritic filopodia. Recruited to actin-patches that seed filopodia, binds specifically to plasma membrane sections that are deformed inward by acto-myosin mediated contractile forces. Acts through GAP activity on RAC1 to reduce actin polymerization necessary for filopodia formation (By similarity. In association with SHANK3, promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation (By similarity.,ARHGAP44,NPC-A-10,RICH2,Signal Transduction,G protein signaling,Signal Transduction,ARHGAP44
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分子量
- 83 kDa/88 kDa/89 kDa
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基因ID
- 9912
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UniProt
- Q17R89
抗原
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