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APLP2 抗体 (AA 340-450)

This anti-APLP2 antibody is a 兔 多克隆 antibody detecting APLP2 in WB 和 IF. Suitable for 人.
产品编号 ABIN6136995
发货至: 中国

Quick Overview for APLP2 抗体 (AA 340-450) (ABIN6136995)

抗原

See all APLP2 抗体
APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

适用

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宿主

  • 69
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克隆类型

  • 67
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多克隆

标记

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This APLP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 340-450

    序列

    RADMDQFTAS ISETPVDVRV SSEESEEIPP FHPFHPFPAL PENEGSGVGE QDGGLIGAEE KVINSKNKVD ENMVIDETLD VKEMIFNAER VGGLEEERES VGPLREDFSL S

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 340-450 of human APLP2 (NP_001135750.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

    别名

    APLP2

    背景

    This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.,APLP2,APLP-2,APPH,APPL2,CDEBP,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,APLP2

    分子量

    59 kDa/79 kDa/80 kDa/85 kDa/86 kDa/87 kDa

    基因ID

    334

    UniProt

    Q06481

    途径

    EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour
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