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APITD1 抗体 (AA 1-138)

This anti-APITD1 antibody is a 兔 多克隆 antibody detecting APITD1 in WB. Suitable for 人.
产品编号 ABIN6136987
发货至: 中国

Quick Overview for APITD1 抗体 (AA 1-138) (ABIN6136987)

抗原

See all APITD1 抗体
APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

适用

  • 13
  • 8
  • 1

宿主

  • 11
  • 2

克隆类型

  • 12
  • 1
多克隆

标记

  • 8
  • 1
  • 1
  • 1
  • 1
  • 1
This APITD1 antibody is un-conjugated

应用范围

  • 12
  • 10
  • 8
  • 8
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-138

    序列

    MEEEAETEEQ QRFSYQQRLK AAVHYTVGCL CEEVALDKEM QFSKQTIAAI SELTFRQCEN FAKDLEMFAR HAKRTTINTE DVKLLARRSN SLLKYITDKS EEIAQINLER KAQKKKKSED GSKNSRQPAE AGVVESEN

    交叉反应

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human APITD1 (NP_954988.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    APITD1 (Apoptosis-Inducing, TAF9-Like Domain 1 (APITD1))

    别名

    APITD1

    背景

    This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7.,CENPS,APITD1,CENP-S,FAAP16,MHF1,Cell Biology & Developmental Biology,Cell Cycle,Centromere,APITD1

    分子量

    9 kDa/15 kDa/19 kDa

    基因ID

    378708

    UniProt

    Q8N2Z9
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