ANTXR1 抗体 (AA 84-333)
Quick Overview for ANTXR1 抗体 (AA 84-333) (ABIN6136913)
抗原
See all ANTXR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 84-333
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序列
- VFSTRGTTLM KLTEDREQIR QGLEELQKVL PGGDTYMHEG FERASEQIYY ENRQGYRTAS VIIALTDGEL HEDLFFYSER EANRSRDLGA IVYCVGVKDF NETQLARIAD SKDHVFPVND GFQALQGIIH SILKKSCIEI LAAEPSTICA GESFQVVVRG NGFRHARNVD RVLCSFKIND SVTLNEKPFS VEDTYLLCPA PILKEVGMKA ALQVSMNDGL SFISSSVIIT TTHCSLHKIA SGPTTAACME
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 84-333 of human ANTXR1 (NP_060623.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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别名
- ANTXR1
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背景
- This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.,ANTXR1,ATR,GAPO,TEM8,Cardiovascular,Angiogenesis,ANTXR1
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分子量
- 33 kDa/37 kDa/39 kDa/41 kDa/59 kDa/62 kDa
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基因ID
- 84168
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UniProt
- Q9H6X2
抗原
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