ALKBH8 抗体 (AA 1-230)
Quick Overview for ALKBH8 抗体 (AA 1-230) (ABIN6136811)
抗原
See all ALKBH8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-230
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序列
- MDSNHQSNYK LSKTEKKFLR KQIKAKHTLL RHEGIETVSY ATQSLVVANG GLGNGVSRNQ LLPVLEKCGL VDALLMPPNK PYSFARYRTT EESKRAYVTL NGKEVVDDLG QKITLYLNFV EKVQWKELRP QALPPGLMVV EEIISSEEEK MLLESVDWTE DTDNQNSQKS LKHRRVKHFG YEFHYENNNV DKDKPLSGGL PDICESFLEK WLRKGYIKHK PDQMTINQYE
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human ALKBH8 (NP_620130.2).
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亚型
- IgG
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anti-AlkB, Alkylation Repair Homolog 8 (ALKBH8) antibody
ALKBH8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 8 (ALKBH8) (AA 494-523), (C-Term) antibodyALKBH8 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19549 unconjugated
anti-AlkB, Alkylation Repair Homolog 8 (ALKBH8) (AA 1-230) antibodyALKBH8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 8 (ALKBH8) (AA 141-190) antibodyALKBH8 适用: 人, 小鼠, 豚鼠, 马, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 8 (ALKBH8) (N-Term) antibodyALKBH8 适用: 人, 豚鼠, 马, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
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别名
- ALKBH8
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背景
- Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg and tRNA(Glu, and does not bind tRNA(Lys(PubMed:20308323. Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S-methoxycarbonylhydroxymethyluridine, has a preference for tRNA(Gly. Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.,ALKBH8,ABH8,TRM9,TRMT9,Epigenetics & Nuclear Signaling,Cancer,Tumor biomarkers,ALKBH8
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分子量
- 25 kDa/27 kDa/75 kDa
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基因ID
- 91801
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UniProt
- Q96BT7
抗原
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