ALKBH5 抗体 (AA 245-394)
Quick Overview for ALKBH5 抗体 (AA 245-394) (ABIN6136806)
抗原
See all ALKBH5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 245-394
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序列
- SLPVRRGSVT VLSGYAADEI THCIRPQDIK ERRAVIILRK TRLDAPRLET KSLSSSVLPP SYASDRLSGN NRDPALKPKR SHRKADPDAA HRPRILEMDK EENRRSVLLP THRRRGSFSS ENYWRKSYES SEDCSEAAGS PARKVKMRRH
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 245-394 of human ALKBH5 (NP_060228.3).
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亚型
- IgG
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anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 302-330) antibody
ALKBH5 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB38474 unconjugated
anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 1-458) antibodyALKBH5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (Internal Region) antibodyALKBH5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
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别名
- ALKBH5
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背景
- Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6-methyladenosine (m6A RNA, the most prevalent internal modification of messenger RNA (mRNA in higher eukaryotes. Can also demethylate N(6-methyladenosine in single-stranded DNA (in vitro. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells (By similarity.,ALKBH5,ABH5,OFOXD,OFOXD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RNA Binding,ALKBH5
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分子量
- 43 kDa/44 kDa/52 kDa
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基因ID
- 54890
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UniProt
- Q6P6C2
抗原
-
