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ACLY 抗体 (pSer455)

This anti-ACLY antibody is a 兔 多克隆 antibody detecting ACLY in WB, IHC 和 IP. Suitable for 人.
产品编号 ABIN6136002
发货至: 中国

Quick Overview for ACLY 抗体 (pSer455) (ABIN6136002)

抗原

See all ACLY 抗体
ACLY (ATP Citrate Lyase (ACLY))

适用

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宿主

  • 85
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克隆类型

  • 71
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多克隆

标记

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This ACLY antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 抗原表位

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    pSer455

    序列

    TASFS

    交叉反应

    小鼠, 大鼠

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic phosphorylated peptide around S455 of human ACLY (NP_001087.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IP,1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ACLY (ATP Citrate Lyase (ACLY))

    别名

    ACLY

    背景

    ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,ACLY,ACL,ATPCL,CLATP,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,Protein phosphorylation,ACLY

    分子量

    91 kDa/119 kDa/120 kDa

    基因ID

    47

    UniProt

    P53396

    途径

    Warburg Effect
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