ACLY 抗体 (pSer455)
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北京 101111
Quick Overview for ACLY 抗体 (pSer455) (ABIN6136002)
抗原
See all ACLY 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer455
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序列
- TASFS
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交叉反应
- 小鼠, 大鼠
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产品特性
- Phosphorylated Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic phosphorylated peptide around S455 of human ACLY (NP_001087.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IP,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ACLY (ATP Citrate Lyase (ACLY))
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别名
- ACLY
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背景
- ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,ACLY,ACL,ATPCL,CLATP,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,Protein phosphorylation,ACLY
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分子量
- 91 kDa/119 kDa/120 kDa
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基因ID
- 47
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UniProt
- P53396
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途径
- Warburg Effect
抗原
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