SH3PXD2A 抗体
Our Local Distributor
北京 101111
Quick Overview for SH3PXD2A 抗体 (ABIN6135104)
抗原
See all SH3PXD2A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 小鼠
-
产品特性
- Polyclonal Antibodies
-
免疫原
- A synthetic peptide of human SH3PXD2A
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
-
别名
- SH3PXD2A
-
背景
- Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs, NADPH oxidases (NOXs and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.,SH3PXD2A,FISH,SH3MD1,TKS5,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,SH3PXD2A
-
分子量
- 102 kDa/121 kDa/125 kDa
-
基因ID
- 9644
-
UniProt
- Q5TCZ1
抗原
-