TCR gamma/delta 抗体
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北京 101111
Quick Overview for TCR gamma/delta 抗体 (ABIN611633)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Rt TCR gamma/delta Purified
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特异性
- The mouse monoclonal antibody V65 recognizes an extracellular epitope of TCR gamma/delta, the subtype of T cell receptor expressed mainly in epithelial tissues and at the sites of infection.
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交叉反应 (详细)
- Rat
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- TCR alpha/beta-negative CD3-positive rat T cell hybridoma III.89.1.4 line
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亚型
- IgG1 kappa
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应用备注
- Flow cytometry: Recommended dilution: 1 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Phenotypic and functional characterization of vaginal dendritic cells in a rat model of Candida albicans vaginitis." in: Infection and immunity, Vol. 74, Issue 7, pp. 4282-94, (2006) (PubMed).
: "Sustained pre-TCR expression in Notch1IC-transgenic rats impairs T cell maturation and selection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 12, pp. 7845-52, (2005) (PubMed).
: "MHC II+ CD45+ cells from synovium-rich tissues of normal rats: phenotype, comparison with macrophage and dendritic cell lineages and differentiation into mature dendritic cells in vitro." in: International immunology, Vol. 17, Issue 8, pp. 1103-15, (2005) (PubMed).
: "Identification of a novel natural regulatory CD8 T-cell subset and analysis of its mechanism of regulation." in: Blood, Vol. 104, Issue 10, pp. 3294-301, (2004) (PubMed).
: "Immune response to Mycoplasma pulmonis in nasal mucosa is modulated by the normal microbiota." in: American journal of respiratory cell and molecular biology, Vol. 31, Issue 6, pp. 657-62, (2004) (PubMed).
: "Zinc-deficient rats have fewer recent thymic emigrant (CD90+) T lymphocytes in spleen and blood." in: The Journal of nutrition, Vol. 133, Issue 12, pp. 4239-42, (2003) (PubMed).
: "Novel monoclonal antibodies against membrane structures that are preferentially expressed on IL-2-activated rat NK cells." in: Journal of leukocyte biology, Vol. 63, Issue 2, pp. 209-15, (1998) (PubMed).
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: "Phenotypic and functional characterization of vaginal dendritic cells in a rat model of Candida albicans vaginitis." in: Infection and immunity, Vol. 74, Issue 7, pp. 4282-94, (2006) (PubMed).
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- TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
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别名
- TCR gamma/delta
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背景
- The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.,TCRG/D
抗原
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