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IL-17 抗体

This 大鼠 单克隆 antibody specifically detects IL-17 in WB, IHC, ELISA, FACS 和 IHC (p). It exhibits reactivity toward 小鼠.
产品编号 ABIN604996
发货至: 中国
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Room 801-803
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Quick Overview for IL-17 抗体 (ABIN604996)

抗原

See all IL-17 (IL17) 抗体
IL-17 (IL17) (Interleukin 17 (IL17))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This IL-17 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

TC11-18H10
  • 特异性

    Recognizes mouse Interleukin 17, a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.

    纯化方法

    Purified from ascites.

    免疫原

    E. coli-expressed, recombinant mouse IL-17A

    亚型

    IgG1
  • 应用备注

    Approved: ELISA, Flo, IHC, IHC-P (10 μg/mL), WB

    Usage: ELISA: This antibody can be used in a sandwich ELISA with LS-C41752 as a detection antibody.

    说明

    Target Species of Antibody: Mouse

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Borate buffered saline.

    注意事项

    Minimize freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20°C. Avoid freeze-thaw cycles.
  • 抗原

    IL-17 (IL17) (Interleukin 17 (IL17))

    别名

    IL17 / IL-17

    背景

    Name/Gene ID: IL17

    Synonyms: IL17
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