IL-17 抗体
Quick Overview for IL-17 抗体 (ABIN604996)
抗原
See all IL-17 (IL17) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- IHC-plus™
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特异性
- Recognizes mouse Interleukin 17, a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.
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纯化方法
- Purified from ascites.
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免疫原
- E. coli-expressed, recombinant mouse IL-17A
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亚型
- IgG1
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应用备注
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Approved: ELISA, Flo, IHC, IHC-P (10 μg/mL), WB
Usage: ELISA: This antibody can be used in a sandwich ELISA with LS-C41752 as a detection antibody. -
说明
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Target Species of Antibody: Mouse
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Borate buffered saline.
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注意事项
- Minimize freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C. Avoid freeze-thaw cycles.
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- IL-17 (IL17) (Interleukin 17 (IL17))
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别名
- IL17 / IL-17
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背景
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Name/Gene ID: IL17
Synonyms: IL17
抗原
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