RIP2 抗体 (Ser176)
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北京 101111
Quick Overview for RIP2 抗体 (Ser176) (ABIN5962657)
抗原
See all RIP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser176
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特异性
- CARD 3,CARD carrying kinase,CARD containing ICE associated kinase,CARD containing IL 1 beta ICE kinase,CARD containing IL1 beta ICE kinase,CARD containing interleukin 1 beta converting enzyme (ICE) associated kinase,CARD containing interleukin 1 beta converting enzyme associated kinase,CARD-containing IL-1 beta ICE-kinase,CARD-containing interleukin-1 beta-converting enzyme-associated kinase,CARD3,CARDIAK,CCK,CLARP kinase,GIG 30,GIG30,Growth inhibiting gene 30,Receptor interacting protein (RIP) like interacting caspase like apoptosis regulatory protein (CLARP) kinase,Receptor interacting protein 2,Receptor interacting serine threonine kinase 2,Receptor interacting serine/threonine protein kinase 2,Receptor-interacting protein 2,Receptor-interacting serine/threonine-protein kinase 2,RICK,RIP 2,RIP like interacting CLARP kinase,RIP-2,RIP-like-interacting CLARP kinase,RIPK 2,Ripk2,RIPK2,TNFRSF,Tyrosine-protein kinase RIPK2,UNQ277/PRO314/PRO34092
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from human RIP2 around the non-phosphorylation site of Ser176.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- RIP2 (ROP Interactive Partner 2 (RIP2))
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别名
- RIP2
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背景
- This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.RIPK2 (Receptor Interacting Serine/Threonine Kinase 2) is a Protein Coding gene. Diseases associated with RIPK2 include Lymphoproliferative Syndrome, X-Linked, 2 and Human Granulocytic Anaplasmosis. Among its related pathways are IL-1 signaling pathway and Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways. GO annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is RIPK4.
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分子量
- 61kDa
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基因ID
- 8767
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UniProt
- O43353
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途径
- TCR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades
抗原
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