GABBR1 抗体
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北京 101111
Quick Overview for GABBR1 抗体 (ABIN5961044)
抗原
See all GABBR1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- DJ271M21.1.1,dJ271M21.1.2,FLJ92613,GABA-B receptor 1,GABA-B-R1,GABA-BR1,GABAB R1,GABAB subunit 1c,GABABR1,GABBR1 3,GABBR1,GABR1,Gamma aminobutyric acid (GABA) B receptor 1,Gamma-aminobutyric acid type B receptor subunit 1,Gb1,GPRC3A,Seven transmembrane helix receptor
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from the C-terminal region of human GABAB R1
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
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别名
- GABAB R1
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背景
- Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants.
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分子量
- 108kDa
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基因ID
- 2550
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UniProt
- Q9UBS5
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途径
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process
抗原
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