PDGFRB 抗体 (Tyr751)
Our Local Distributor
北京 101111
Quick Overview for PDGFRB 抗体 (Tyr751) (ABIN5960495)
抗原
See all PDGFRB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Tyr751
-
特异性
- Beta platelet derived growth factor receptor,Beta-type platelet-derived growth factor receptor,CD 140B,CD140 antigen-like family member B,CD140b,CD140b antigen,IBGC4,IMF1,JTK12,OTTHUMP00000160528,PDGF R beta,PDGF-R-beta,PDGFR 1,PDGFR,PDGFR beta,PDGFR1,PDGFRB,PGFRB,Platelet derived growth factor receptor 1,Platelet derived growth factor receptor beta,Platelet derived growth factor receptor beta polypeptide
-
纯化方法
- Affinity purification
-
免疫原
- Synthesized peptide derived from human PDGFR-beta around the non-phosphorylation site of Tyr751.
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
-
别名
- PDGFRB
-
背景
- This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
-
分子量
- 124kDa
-
基因ID
- 5159
-
UniProt
- P09619
-
途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
-