Myosin VI 抗体
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北京 101111
Quick Overview for Myosin VI 抗体 (ABIN5958676)
抗原
See all Myosin VI (MYO6) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Deafness autosomal recessive 37,DFNA 22,DFNA22,DFNB 37,DFNB37,KIAA0389,MYO 6,Myo6,MYO6,Myosin VI,Myosin-VI,Myosin6,Unconventional myosin-6,Unconventional myosin-VI
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from the N-terminal region of human Myosin VI
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:100-300, ELISA 1:5000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Myosin VI (MYO6)
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别名
- Myosin VI
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背景
- This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. MYO6 (Myosin VI) is a Protein Coding gene. Diseases associated with MYO6 include Deafness, Autosomal Dominant 22 and Deafness, Autosomal Recessive 37. Among its related pathways are PAK Pathway and Vesicle-mediated transport. GO annotations related to this gene include actin binding and actin filament binding. An important paralog of this gene is MYO7A.
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分子量
- 150kDa
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基因ID
- 4646
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UniProt
- Q9UM54
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途径
- Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization
抗原
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