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Myosin VI 抗体

The 兔 多克隆 anti-Myosin VI antibody (ABIN5958676) specifically detects Myosin VI in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN5958676
发货至: 中国
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Quick Overview for Myosin VI 抗体 (ABIN5958676)

抗原

See all Myosin VI (MYO6) 抗体
Myosin VI (MYO6)

适用

  • 19
  • 19
  • 18
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 32
  • 2

克隆类型

  • 32
  • 2
多克隆

标记

  • 15
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Myosin VI antibody is un-conjugated

应用范围

  • 19
  • 17
  • 13
  • 13
  • 11
  • 8
  • 8
  • 6
  • 3
  • 2
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    Deafness autosomal recessive 37,DFNA 22,DFNA22,DFNB 37,DFNB37,KIAA0389,MYO 6,Myo6,MYO6,Myosin VI,Myosin-VI,Myosin6,Unconventional myosin-6,Unconventional myosin-VI

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from the N-terminal region of human Myosin VI

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-300, ELISA 1:5000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Myosin VI (MYO6)

    别名

    Myosin VI

    背景

    This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. MYO6 (Myosin VI) is a Protein Coding gene. Diseases associated with MYO6 include Deafness, Autosomal Dominant 22 and Deafness, Autosomal Recessive 37. Among its related pathways are PAK Pathway and Vesicle-mediated transport. GO annotations related to this gene include actin binding and actin filament binding. An important paralog of this gene is MYO7A.

    分子量

    150kDa

    基因ID

    4646

    UniProt

    Q9UM54

    途径

    Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization
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