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Caspase 5 p20 抗体 (Cleaved-Asp121)

The 兔 多克隆 anti-Caspase 5 p20 antibody (ABIN5955946) specifically detects Caspase 5 p20 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN5955946
发货至: 中国
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Quick Overview for Caspase 5 p20 抗体 (Cleaved-Asp121) (ABIN5955946)

抗原

Caspase 5 p20

适用

  • 3
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宿主

  • 3

克隆类型

  • 3
多克隆

标记

  • 3
This Caspase 5 p20 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA
  • 抗原表位

    • 1
    • 1
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    Cleaved-Asp121

    特异性

    Apoptosis related cysteine protease,CASP-5,CASP5,CASP5,Caspase-5 subunit p10,ICE(rel)-III,ICERELIII,ICH 3,ICH 3 protease,Protease ICH-3,Protease TY,TY,TY protease

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from the Internal region of human Caspase-5 p20

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA 1:20000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Caspase 5 p20

    别名

    Caspase-5 p20

    背景

    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

    分子量

    48kDa

    基因ID

    838

    UniProt

    P51878
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