Caspase 5 p10 抗体 (Cleaved-Ser331)
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Quick Overview for Caspase 5 p10 抗体 (Cleaved-Ser331) (ABIN5955945)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Ser331
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特异性
- Apoptosis related cysteine protease,CASP-5,CASP5,CASP5,Caspase-5 subunit p10,ICE(rel)-III,ICERELIII,ICH 3,ICH 3 protease,Protease ICH-3,Protease TY,TY,TY protease
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from the C-terminal region of human Caspase-5 p10
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, ELISA 1:20000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Caspase 5 p10
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别名
- Caspase-5 p10
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背景
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
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分子量
- 48kDa
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基因ID
- 838
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UniProt
- P51878
抗原
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