3 phosphoinositide dependent protein kinase 1,3-phosphoinositide-dependent protein kinase 1,hPDK 1,hPDK1,MGC20087,MGC35290,OTTHUMP00000159109,OTTHUMP00000159110,OTTHUMP00000174525,PDK1,Pdpk1,PDPK1,PDPK2,PDPK2P,PkB kinase,PkB kinase like gene 1,PkB like 1,PRO0461,Protein kinase
纯化方法
Affinity purification
免疫原
Synthesized peptide derived from human PDK1 around the non-phosphorylation site of Ser241.
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
PDPK1
(3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
别名
PDPK1
背景
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.