Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
3 phosphoinositide dependent protein kinase 1,3-phosphoinositide-dependent protein kinase 1,hPDK 1,hPDK1,MGC20087,MGC35290,OTTHUMP00000159109,OTTHUMP00000159110,OTTHUMP00000174525,PDK1,Pdpk1,PDPK1,PDPK2,PDPK2P,PkB kinase,PkB kinase like gene 1,PkB like 1,PRO0461,Protein kinase
纯化方法
Affinity purification
免疫原
Synthesized peptide derived from human PDK1 around the non-phosphorylation site of Ser241.
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.