FH 抗体 (AA 44-510)
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北京 101111
Quick Overview for FH 抗体 (AA 44-510) (ABIN5776268)
抗原
See all FH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 44-510
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原理
- Human Fumarase/FH antibody
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纯化方法
- Purified
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免疫原
- Recombinant human Fumarase (44-510aa) purified from E. coli
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亚型
- IgG2a kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- FH (Fumarate Hydratase (FH))
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别名
- Fumarase/FH
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背景
- Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor.
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NCBI登录号
- NP_000134
抗原
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