GALE 抗体 (AA 1-348)
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Quick Overview for GALE 抗体 (AA 1-348) (ABIN5776219)
抗原
See all GALE 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-348
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原理
- Human UDP-galactose-4-epimerase/GALE antibody
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纯化方法
- Purified
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免疫原
- Recombinant human GALE (1-348aa) purified from E. coli
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亚型
- IgG1 kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- GALE (UDP-Galactose-4-Epimerase (GALE))
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别名
- UDP-galactose-4-epimerase/GALE
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背景
- The enzyme UDP-glucose 4-epimerase, also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This enzyme performs the final step in the Leloir pathway of galactose metabolism, catalyzing the reversible conversion of UDP-galactose to UDP-glucose. GALE tightly binds nicotinamide adenine dinucleotide (NAD+), a co-factor required for catalytic activity. Additionally, human and some bacterial GALE isoforms reversibly catalyze the formation of UDP-N-acetylgalactosamine (UDP-GalNAc) from UDP-N-acetylglucosamine (UDP-GlcNAc) in the presence of NAD+, an initial step in glycoprotein or glycolipid synthesis.
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NCBI登录号
- NP_000394
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途径
- Response to Water Deprivation, Cellular Glucan Metabolic Process
抗原
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