GCLM 抗体 (AA 1-274)
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Quick Overview for GCLM 抗体 (AA 1-274) (ABIN5776191)
抗原
See all GCLM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-274
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原理
- Human GCLM antibody
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纯化方法
- Purified
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免疫原
- Recombinant human GCLM (1-274aa) purified from E. coli
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亚型
- IgG1 kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
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别名
- GCLM
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背景
- GCLM (Glutamate-cysteine ligase, modifier subunit), also known as gamma-glutamylcysteine synthetase, is first rate limiting enzyme of glutathione synthesis. GCLM is heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. GCLM deficiency has been implicated in some forms of hemolytic anemia. Also, GCLM is a molecular target for amelioration of cisplatin restance in lung cancer.
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NCBI登录号
- NP_002052
抗原
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