DECR1 抗体 (AA 35-335)
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Quick Overview for DECR1 抗体 (AA 35-335) (ABIN5776166)
抗原
See all DECR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 35-335
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原理
- Human DECR1 antibody
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纯化方法
- Purified
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免疫原
- Recombinant human DECR1 (35-335aa) purified from E. coli
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亚型
- IgG2b kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- DECR1 (2,4-Dienoyl CoA Reductase 1, Mitochondrial (DECR1))
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别名
- DECR1
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背景
- DECR1 is a mitochondrial protein that exists as a homotetramer and belongs to the family of short-chain dehydrogenases/reductases. It functions as an auxiliary enzyme of beta-oxidation andt participates in the metabolism of unsaturated fatty enoyl-CoA esters. Specifically, DECR1 uses NADP+ to catalyze the reduction of 2, 4-dienoyl-CoA to yield trans-3-enoyl-CoA, which can then be used as an intermediate in the Krebs cycle. Additionally, DECR1 is thought to function as a tumor suppressor, possibly downregulating the expression of Neu and slowing the rate of tumorigenesis.
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NCBI登录号
- NP_001350
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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