RAS 抗体 (AA 1-186)
This 小鼠 单克隆 antibody specifically detects RAS in WB, IF, ICC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN5776161
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for RAS 抗体 (AA 1-186) (ABIN5776161)
抗原
RAS
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This RAS antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA
克隆位点
AT2F8
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抗原表位
- AA 1-186
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原理
- Human Ras antibody
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纯化方法
- Purified
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免疫原
- Recombinant human KRAS (1-186aa) purified from E. coli
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亚型
- IgG2b kappa
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anti-RAS (RAS) (AA 1-186) antibody
RAS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT2G9 unconjugated
anti-RAS (RAS) (pan) antibodyRAS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- RAS
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别名
- Ras
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背景
- All RAS protein family members belong to a class of protein called small GTPase, and are involved cellular signal transduction. RAS is 'switched on' by incoming signals, it subsequently switches on other proteins, which ultimately turn on genes involved in cell growth, differentiation and survival. Mutations in RAS genes can lead to the production of permanently activated RAS proteins. This can cause unintended and overactive signaling inside the cell, even in the absence of incoming signals. Because these signals result in cell growth and division, overactive RAS signaling can ultimately lead to cancer. The 3 Ras genes in humans (HRas, KRas, NRas) are the most common oncogenes in human cancer, mutations that permanently activate RAS are found in 20 % to 25 % of all human tumors and up to 90 % in certain types of cancer. RAS inhibitors are being studied as a treatment for cancer, and other diseases with RAS overexpression.
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NCBI登录号
- NP_203524
抗原
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