RAS 抗体 (AA 1-186)
This anti-RAS antibody is a 小鼠 单克隆 antibody detecting RAS in WB, ELISA, IF 和 ICC. Suitable for 人.
Quick Overview for RAS 抗体 (AA 1-186) (ABIN5776161)
抗原
RAS
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This RAS antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
克隆位点
AT2F8
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抗原表位
- AA 1-186
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免疫原
- Recombinant human KRAS (1-186aa) purified from E. coli
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亚型
- IgG2b kappa
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anti-RAS (RAS) (AA 1-186) antibody
RAS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT2G9 unconjugated
anti-RAS (RAS) (pan) antibodyRAS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- RAS
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别名
- Ras
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背景
- All RAS protein family members belong to a class of protein called small GTPase, and are involved cellular signal transduction. RAS is 'switched on' by incoming signals, it subsequently switches on other proteins, which ultimately turn on genes involved in cell growth, differentiation and survival. Mutations in RAS genes can lead to the production of permanently activated RAS proteins. This can cause unintended and overactive signaling inside the cell, even in the absence of incoming signals. Because these signals result in cell growth and division, overactive RAS signaling can ultimately lead to cancer. The 3 Ras genes in humans (HRas, KRas, NRas) are the most common oncogenes in human cancer, mutations that permanently activate RAS are found in 20 % to 25 % of all human tumors and up to 90 % in certain types of cancer. RAS inhibitors are being studied as a treatment for cancer, and other diseases with RAS overexpression.
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NCBI登录号
- NP_203524
抗原
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