YWHAE 抗体 (AA 1-255)
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Quick Overview for YWHAE 抗体 (AA 1-255) (ABIN5776144)
抗原
See all YWHAE 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-255
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原理
- Human 14-3-3 epsilon antibody
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纯化方法
- Purified
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免疫原
- Recombinant human14-3-3 epsilon (1-255aa) purified from E. coli
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亚型
- IgG2b kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- YWHAE (14-3-3 epsilon (YWHAE))
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别名
- 14-3-3 epsilon
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背景
- The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer.
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NCBI登录号
- NP_006752
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途径
- Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
抗原
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