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PA2G4 抗体 (AA 1-394)

This anti-PA2G4 antibody is a 小鼠 单克隆 antibody detecting PA2G4 in WB, ELISA, IF, FACS 和 ICC. Suitable for 人.
产品编号 ABIN5776098
发货至: 中国

Quick Overview for PA2G4 抗体 (AA 1-394) (ABIN5776098)

抗原

See all PA2G4 抗体
PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

适用

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宿主

  • 59
  • 5
小鼠

克隆类型

  • 51
  • 13
单克隆

标记

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  • 1
  • 1
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This PA2G4 antibody is un-conjugated

应用范围

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  • 9
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

AT5E7
  • 抗原表位

    • 15
    • 6
    • 6
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    • 2
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    • 1
    • 1
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    AA 1-394

    原理

    Human PA2G4 antibody

    纯化方法

    Purified

    免疫原

    Recombinant human PA2G4 (1-394aa) purified from E. coli

    亚型

    IgG1 kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • 抗原

    PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

    别名

    PA2G4

    背景

    PA2G4 may play a role in a ERBB3-regulated signal transduction pathway and seems be involved in growth regulation. This protein acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Also, this protein Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity, and binds RNA. The protein is associated with 28S, 18S and 5. 8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA, that may be involved in regulation of intermediate and late steps of rRNA processing, and may be involved in ribosome assembly. The protein mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity), and regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity).

    NCBI登录号

    NP_006182

    途径

    Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades
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