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AKR1C1 抗体 (AA 1-323)

This 小鼠 单克隆 antibody specifically detects AKR1C1 in WB, ELISA, IF, ICC 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN5776092
发货至: 中国
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Quick Overview for AKR1C1 抗体 (AA 1-323) (ABIN5776092)

抗原

See all AKR1C1 (DDH) 抗体
AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

适用

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宿主

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小鼠

克隆类型

  • 34
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单克隆

标记

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This AKR1C1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

AT6D10
  • 抗原表位

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    AA 1-323

    原理

    Human Aldo-keto Reductase 1C1/AKR1C1 antibody

    纯化方法

    Purified

    免疫原

    Recombinant human AKR1C1 (1-323aa) purified from E. coli

    亚型

    IgG1 kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • 抗原

    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

    别名

    Aldo-keto Reductase 1C1/AKR1C1

    背景

    The human aldo-keto reductases 1C1 and 1C3 (AKR1C1 and AKR1C3) have major roles in pre receptor regulation of progesterone action. They can both convert progesterone to the less potent efficiencies. AKR1C1 and AKR1C3 also act as 3-ketosteroid reductase, and as such they can convert the most potent androgen 5alpha-DHT into 3beta-andorstandiol, which is an estrogen receptor beta ligand, and into the inactive androgen 3alpha-androstnionl, respectively.

    NCBI登录号

    NP_001344

    途径

    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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