AKR1C1 抗体 (AA 1-323)
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Quick Overview for AKR1C1 抗体 (AA 1-323) (ABIN5776092)
抗原
See all AKR1C1 (DDH) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-323
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原理
- Human Aldo-keto Reductase 1C1/AKR1C1 antibody
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纯化方法
- Purified
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免疫原
- Recombinant human AKR1C1 (1-323aa) purified from E. coli
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亚型
- IgG1 kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
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别名
- Aldo-keto Reductase 1C1/AKR1C1
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背景
- The human aldo-keto reductases 1C1 and 1C3 (AKR1C1 and AKR1C3) have major roles in pre receptor regulation of progesterone action. They can both convert progesterone to the less potent efficiencies. AKR1C1 and AKR1C3 also act as 3-ketosteroid reductase, and as such they can convert the most potent androgen 5alpha-DHT into 3beta-andorstandiol, which is an estrogen receptor beta ligand, and into the inactive androgen 3alpha-androstnionl, respectively.
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NCBI登录号
- NP_001344
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途径
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
抗原
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