KRT8 抗体 (AA 1-483)
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北京 101111
Quick Overview for KRT8 抗体 (AA 1-483) (ABIN5776086)
抗原
See all KRT8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-483
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原理
- Human Keratin 8/KRT8 antibody
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纯化方法
- Purified
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免疫原
- Recombinant human KRT8 (1-483aa) purified from E. coli
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亚型
- IgG3 kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- KRT8 (Keratin 8 (KRT8))
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别名
- Keratin 8/KRT8
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背景
- Keratin, type II cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that in human is encoded by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
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NCBI登录号
- NP_002264
抗原
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