KRT17 抗体 (AA 1-432)
Quick Overview for KRT17 抗体 (AA 1-432) (ABIN5776077)
抗原
See all KRT17 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-432
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免疫原
- Recombinant human KRT17(1-432aa) purified from E. coli
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亚型
- IgG2a kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- KRT17 (Keratin 17 (KRT17))
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别名
- Cytokeratin 17/KRT17
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背景
- Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments. Keratin 17 is involved in wound healing and cell growth, two processes that require rapid cytoskeletal remodeling. Keratinocytes deficient in keratin 17 exhibit abnormal Akt/mTOR signaling and fail to produce an increase in translation, cell size, or growth, these cells also exhibit abnormal 14-3-3 sigma localization.
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NCBI登录号
- NP_000413
抗原
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