beta-2 Microglobulin 抗体 (AA 21-119)
Quick Overview for beta-2 Microglobulin 抗体 (AA 21-119) (ABIN5776062)
抗原
See all beta-2 Microglobulin (B2M) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 21-119
-
免疫原
- Recombinant human B2M (21-119aa) purified from E. coli
-
亚型
- IgG2b kappa
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
-
-
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
-
别名
- beta 2-Microglobulin/B2M
-
背景
- Beta2 microglobulin, also known as B2M, is a component of MHC class I molecules, Involved in the presentation of peptide antigens to the immune system. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Increased production or destruction of these cells causes B2M levels in the blood to increase. This increase is seen in people with cancers involving white blood cells, but it is particularly meaningful in people newly diagnosed with multiple myeloma. Multiple myeloma is a malignancy (cancer) of a certain kind of white blood cell, called a plasma cell. B2M Testing is done primarily when evaluating a person for certain kinds of cancer affecting white blood cells including chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and multiple myeloma or kidney disease.
-
NCBI登录号
- NP_004039
-
途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
-