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NQO2 抗体 (AA 1-231)

This anti-NQO2 antibody is a 小鼠 单克隆 antibody detecting NQO2 in WB, ELISA, IF 和 ICC. Suitable for 人.
产品编号 ABIN5776048
发货至: 中国

Quick Overview for NQO2 抗体 (AA 1-231) (ABIN5776048)

抗原

See all NQO2 抗体
NQO2

适用

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宿主

  • 55
  • 8
  • 2
小鼠

克隆类型

  • 49
  • 16
单克隆

标记

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This NQO2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

AT1E3
  • 抗原表位

    • 14
    • 9
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    • 4
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    • 1
    • 1
    • 1
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    • 1
    AA 1-231

    免疫原

    Recombinant human NQO2 (1-231aa) purified from E. coli

    亚型

    IgG1 kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    NQO2

    别名

    NQO2

    背景

    Quinone oxidoreductase (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic redaction of quinines and derivates. NQO2 is inhibited by flavones such as quercetin. Also benzo (a) pyrene is another known inhibitor of NQO2. Even though overlapping substrates specificities have been observed for NQO1 and NQO2, such as for CB1954 activation, significant differences exist in relative affinities for the various substrates. The detoxification role of NQO2 has not been found, and it has no known endogenous biological substrates. However, NQO1 plays an important role in the detoxification of various endogenous and exogenous quinones, including estrogen quinines. Also NQO2 has a melatonin-binding site, which may explain the anti-oxidant role of melatonin related with circadian rhythm.
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