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TYMS 抗体 (AA 1-313)

This anti-TYMS antibody is a 小鼠 单克隆 antibody detecting TYMS in WB, IF, FACS, ELISA 和 ICC. Suitable for 人.
产品编号 ABIN5776023
发货至: 中国

Quick Overview for TYMS 抗体 (AA 1-313) (ABIN5776023)

抗原

See all TYMS 抗体
TYMS (Thymidylate Synthetase (TYMS))

适用

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宿主

  • 64
  • 50
  • 1
小鼠

克隆类型

  • 71
  • 44
单克隆

标记

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  • 1
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This TYMS antibody is un-conjugated

应用范围

  • 62
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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

克隆位点

AT21S5
  • 抗原表位

    • 26
    • 15
    • 13
    • 5
    • 4
    • 3
    • 3
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    • 1
    • 1
    • 1
    • 1
    AA 1-313

    免疫原

    Recombinant TYMS (1-313aa) purified from E. coli

    亚型

    IgG2b kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    TYMS (Thymidylate Synthetase (TYMS))

    别名

    Thymidylate synthase/TYMS

    背景

    The methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dMTP) is an essential step for the formation of thymine nucleotides. This process is catalyzed by thymidylate synthase (TS or TYMS). TYMS is an intracellular enzyme that provides the sole de novo source of thymidylate in activity highest proliferating cells. Being the exclusive source of dTMP, TS is also an important target for anticancer agents such as 5-fluorouracil (5-FU). 5-FU acts as a TS inhibitor and is active against solid tumors such as colon, breast, head and neck. TS expression may be useful in predicting overall patient survival, but the prognostic value of TS expression continues to be a subject of investigation for different types of cancers.

    NCBI登录号

    NP_001062

    途径

    Mitotic G1-G1/S Phases
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