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PKM 抗体 (AA 1-531)

This anti-PKM antibody is a 小鼠 单克隆 antibody detecting PKM in ELISA, WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN5776015
发货至: 中国

Quick Overview for PKM 抗体 (AA 1-531) (ABIN5776015)

抗原

See all PKM 抗体
PKM (Pyruvate Kinase M1/2 (PKM))

适用

  • 44
  • 13
  • 7
  • 4

宿主

  • 42
  • 5
  • 3
小鼠

克隆类型

  • 42
  • 8
单克隆

标记

  • 32
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PKM antibody is un-conjugated

应用范围

  • 31
  • 29
  • 19
  • 13
  • 7
  • 6
  • 5
  • 2
  • 1
ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

AT1B10
  • 抗原表位

    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-531

    免疫原

    Recombinant human PKM2 (1-531aa) purified from E.coli

    亚型

    IgG1 kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    PKM (Pyruvate Kinase M1/2 (PKM))

    别名

    PKM

    背景

    PKM2 (pyruvate kinase M2), its association with phospho-tyrosine (pTyr) motifs, enables cells to use predominantly aerobic glycolysis instead of oxidative phosphorylation. Also PKM2 suggest that this change benefits cancer cells by enabling them to redirect glycolytic metabolites away from oxidation and energy production and, instead, toward anabolic processes and biosynthesis. PKM2-mediated generation of the aerobic glycolytic phenotype, although wasteful in terms of glucose consumption and waste generation, could provide a variety of advantages for cancerous cells. In addition nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death.

    NCBI登录号

    NP_002645

    途径

    Warburg Effect
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