Phosphoglucomutase 1 抗体 (AA 1-562)
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Quick Overview for Phosphoglucomutase 1 抗体 (AA 1-562) (ABIN5775973)
抗原
See all Phosphoglucomutase 1 (PGM1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-562
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原理
- Human PGM1 antibody
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纯化方法
- Purified
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免疫原
- Recombinant human PGM1 (1-562aa) purified from E. coli
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亚型
- IgG1 kappa
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anti-Phosphoglucomutase 1 (PGM1) (AA 1-562) antibody
PGM1 适用: 人 WB, IF, ELISA, IP, RNAi 宿主: 小鼠 Monoclonal 3B8-H4 unconjugated
anti-Phosphoglucomutase 1 (PGM1) (AA 1-235) antibodyPGM1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoglucomutase 1 (PGM1) (AA 469-501) antibodyPGM1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB53795 unconjugated
anti-Phosphoglucomutase 1 (PGM1) (AA 1-562) antibodyPGM1 适用: 人 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoglucomutase 1 (PGM1) antibodyKD Validated PGM1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3325 unconjugated Recombinant Antibody
anti-Phosphoglucomutase 1 (PGM1) (AA 1-300) antibodyPGM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphoglucomutase 1 (PGM1) (AA 251-282) antibodyPGM1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB54238 unconjugated
anti-Phosphoglucomutase 1 (PGM1) (AA 1-562) antibodyPGM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphoglucomutase 1 (PGM1) antibodyPGM1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoglucomutase 1 (PGM1) (C-Term) antibodyPGM1 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 斑马鱼, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Phosphoglucomutase 1 (PGM1)
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别名
- PGM1
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背景
- PGM1 is an evolutionarily conserved enzyme that regulates one of the most important metabolic carbohydrate trafficking points in prokaryotic and eukaryotic organisms, catalyzing the bi-directional interconversion of glucose 1-phosphate (G-1-P) and glucose 6-phosphate (G-6-P). In one direction, G-1-P produced from sucrose catabolism is converted to G-6-P, the first intermediate in glycolysis. In the other direction, conversion of G-6-P to G-1-P generates a substrate for synthesis of UDP-glucose, which is required for synthesis of a variety of cellular constituents, including cell wall polymers and glycoproteins. PGM1 has been used extensively as a genetic marker for isozyme polymorphism among humans. PGM is known to be post-translationally modified by cytoplasmic glycosylation that does not seem to regulate its enzymatic activity but rather is implicated in the localization of the protein. Glucose 1, 6 bisphosphate (Glc-1, 6-P2), a powerful regulator of carbohydrate metabolism, has been demonstrated to be a potent activator of PGM. PGM1 is also modified by phosphorylation on Ser108 as part of its catalytic mechanism. This is shown to be performed by Pak1, a previously identified signaling kinase.
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NCBI登录号
- NP_002624
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途径
- Cellular Glucan Metabolic Process
抗原
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