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Phosphoglucomutase 1 抗体 (AA 1-562)

This anti-Phosphoglucomutase 1 antibody is a 小鼠 单克隆 antibody detecting Phosphoglucomutase 1 in WB, ELISA, IF 和 ICC. Suitable for 人.
产品编号 ABIN5775973
发货至: 中国

Quick Overview for Phosphoglucomutase 1 抗体 (AA 1-562) (ABIN5775973)

抗原

See all Phosphoglucomutase 1 (PGM1) 抗体
Phosphoglucomutase 1 (PGM1)

适用

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  • 25
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  • 2
  • 2
  • 1
  • 1
  • 1
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宿主

  • 45
  • 5
  • 4
小鼠

克隆类型

  • 48
  • 5
单克隆

标记

  • 28
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
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  • 1
This Phosphoglucomutase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

AT84G2
  • 抗原表位

    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-562

    免疫原

    Recombinant human PGM1 (1-562aa) purified from E. coli

    亚型

    IgG1 kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    Phosphoglucomutase 1 (PGM1)

    别名

    PGM1

    背景

    PGM1 is an evolutionarily conserved enzyme that regulates one of the most important metabolic carbohydrate trafficking points in prokaryotic and eukaryotic organisms, catalyzing the bi-directional interconversion of glucose 1-phosphate (G-1-P) and glucose 6-phosphate (G-6-P). In one direction, G-1-P produced from sucrose catabolism is converted to G-6-P, the first intermediate in glycolysis. In the other direction, conversion of G-6-P to G-1-P generates a substrate for synthesis of UDP-glucose, which is required for synthesis of a variety of cellular constituents, including cell wall polymers and glycoproteins. PGM1 has been used extensively as a genetic marker for isozyme polymorphism among humans. PGM is known to be post-translationally modified by cytoplasmic glycosylation that does not seem to regulate its enzymatic activity but rather is implicated in the localization of the protein. Glucose 1, 6 bisphosphate (Glc-1, 6-P2), a powerful regulator of carbohydrate metabolism, has been demonstrated to be a potent activator of PGM. PGM1 is also modified by phosphorylation on Ser108 as part of its catalytic mechanism. This is shown to be performed by Pak1, a previously identified signaling kinase.

    NCBI登录号

    NP_002624

    途径

    Cellular Glucan Metabolic Process
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