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Layilin 抗体 (AA 22-235)

The 小鼠 单克隆 anti-Layilin antibody (Clone AT18E10) (ABIN5775959) specifically detects Layilin in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN5775959
发货至: 中国
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Quick Overview for Layilin 抗体 (AA 22-235) (ABIN5775959)

抗原

See all Layilin (LAYN) 抗体
Layilin (LAYN)

适用

  • 26
  • 12
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 18
  • 7
  • 2
小鼠

克隆类型

  • 20
  • 7
单克隆

标记

  • 17
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Layilin antibody is un-conjugated

应用范围

  • 12
  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA

克隆位点

AT18E10
  • 抗原表位

    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 22-235

    原理

    Human Layilin/LAYN antibody

    纯化方法

    Purified

    免疫原

    Recombinant human LAYN (22-235aa) purified from E. coli

    亚型

    IgG1 kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • 抗原

    Layilin (LAYN)

    别名

    Layilin/LAYN

    背景

    Layilin is a widely expressed integral membrane hyaluronan receptor and a transmembrane protein with homology to C-type lectins. This protein interacts with the ERM protein family of cytoskeletal membrane linker molecule members, including talin, ezrin, moesin, and radixin. The carboxy-terminal domain of layilin is capable of binding to the amino-terminal domain of radixin. An interdomain interaction between the amino- and the carboxy-terminal domains of radixin inhibits its ability to bind to layilin. Layilin plays an important role in cell adhesion and motility. It is important for the maintenance of the cortical structure in the cell because it mediates signals from the extracellular matrix to the cytoskeleton. In spreading cells, Layilin acts as a membrane-binding site for talin in the peripheral ruffles, and it may play a role in the migration of cells to a wound site.

    NCBI登录号

    NP_001245319
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