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Layilin 抗体 (AA 22-235)

This anti-Layilin antibody is a 小鼠 单克隆 antibody detecting Layilin in WB 和 ELISA. Suitable for 人.
产品编号 ABIN5775959
发货至: 中国

Quick Overview for Layilin 抗体 (AA 22-235) (ABIN5775959)

抗原

See all Layilin (LAYN) 抗体
Layilin (LAYN)

适用

  • 25
  • 12
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 19
  • 7
小鼠

克隆类型

  • 21
  • 5
单克隆

标记

  • 16
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Layilin antibody is un-conjugated

应用范围

  • 13
  • 11
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA

克隆位点

AT18E10
  • 抗原表位

    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 22-235

    免疫原

    Recombinant human LAYN (22-235aa) purified from E. coli

    亚型

    IgG1 kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    Layilin (LAYN)

    别名

    Layilin/LAYN

    背景

    Layilin is a widely expressed integral membrane hyaluronan receptor and a transmembrane protein with homology to C-type lectins. This protein interacts with the ERM protein family of cytoskeletal membrane linker molecule members, including talin, ezrin, moesin, and radixin. The carboxy-terminal domain of layilin is capable of binding to the amino-terminal domain of radixin. An interdomain interaction between the amino- and the carboxy-terminal domains of radixin inhibits its ability to bind to layilin. Layilin plays an important role in cell adhesion and motility. It is important for the maintenance of the cortical structure in the cell because it mediates signals from the extracellular matrix to the cytoskeleton. In spreading cells, Layilin acts as a membrane-binding site for talin in the peripheral ruffles, and it may play a role in the migration of cells to a wound site.

    NCBI登录号

    NP_001245319
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