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HAX1 抗体 (AA 1-279)

The 小鼠 单克隆 anti-HAX1 antibody is suitable to detect HAX1 in samples from 人. It has been validated for WB, ELISA, IF 和 ICC.
产品编号 ABIN5775949
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HAX1 抗体 (AA 1-279) (ABIN5775949)

抗原

See all HAX1 抗体
HAX1 (HCLS1 Associated Protein X-1 (HAX1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This HAX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

AT3C5
  • 抗原表位

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    AA 1-279

    原理

    Human HAX-1 antibody

    纯化方法

    Purified

    免疫原

    Recombinant human HAX1 (1-279aa) purified from E. coli

    亚型

    IgG2b kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • 抗原

    HAX1 (HCLS1 Associated Protein X-1 (HAX1))

    别名

    HAX-1

    背景

    HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1 (HS1), one of the substrates of receptor-coupled tyrosine kinases activated during clonal expansion and deletion in lymphoid cells. It also interacts with the product of the polycystic kidney disease 2 (PKD2) gene and with the F-actin-binding protein, cortactin. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.

    NCBI登录号

    NP_006109

    途径

    Regulation of Actin Filament Polymerization
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