Cathepsin S 抗体 (AA 17-331)
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Quick Overview for Cathepsin S 抗体 (AA 17-331) (ABIN5775924)
抗原
See all Cathepsin S (CTSS) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 17-331
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原理
- Human Cathepsin S antibody
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纯化方法
- Purified
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免疫原
- Recombinant human CTSS (17-331aa) purified from E. coli
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亚型
- IgG2b kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Cathepsin S (CTSS)
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别名
- Cathepsin S
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背景
- CTSS (Cathepsin S) is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, CTSS is expressed in some epithelial cells. In contrast, cortical thymic epithelial cells do not express CTSS. Normal epidermal keratinocytes do not express CTSS. However, level of CTSS is elevated in psoriatic keratinocytes due to stimulation by proinflammatory factors. CTSS can function as an elastase over a broad pH range in alveolar macrophages.
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NCBI登录号
- NP_004070
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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