Influenza A Virus H1N1 抗体 (N-Term)
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Quick Overview for Influenza A Virus H1N1 抗体 (N-Term) (ABIN576766)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Influenza A virus H1N1 by Hemagglutination inhibition. Thisdoes not react with Influenza B, RSV, Para 1-3 or Adenovirus. It does not react with cells but may react with some chicken cellular proteins. Influenza type A viruses are divided into subtypes based on the antigenic differences of two viral surface proteins, hemagglutinin (H) and neuraminidase (N). On infection of the respiratory tract, the hemagglutinin molecule binds to sialic acid-containing receptors on the epithelial cells resulting in endocytosis. Once the virus has been engulfed, the hemagglutinin allows the viral membrane to fuse with the endosomal membrane. Neuraminidase functions to aid viral release from host cells by cleaving terminal sialic acid residues from carbohydrate moieties on the cell surface. Viral release also requires the interaction of the viral M1 protein with the celular scaffold G-like protein. Subtype antigenic variations result from a process known as antigenic drift whereby these surface proteins constantly mutate in order to evade the host immune response. Subtype A(H1N1) was the cause of that killed approximately 50000000 people between 1918-1919.
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纯化方法
- Purified
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免疫原
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Influenza A, strain USSR (H1N1).
Type of Immunogen: Virus
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Influenza Virus
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Short term: -20°C
Long term: -20°C.
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- Influenza A Virus H1N1
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物质类
- Influenza Virus
抗原
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