CD11b 抗体 (PE)
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- 抗原 See all CD11b (ITGAM) 抗体
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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适用
- 人, 小鼠, 兔
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD11b antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Recognizes the murine CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor. * Clone M1/70.15 has been reported to as being suitable for use on PLP fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue. This product is routinely tested in flow cytometry on mouse peritoneal macrophages.
- 纯化方法
- Protein G purified
- 免疫原
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T cells enriched splenocytes from B10 mice.
Type of Immunogen: Cells - 亚型
- IgG2b
- Top Product
- Discover our top product ITGAM Primary Antibody
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- 应用备注
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Approved: Flo (1:1 - 1:10)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - 说明
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Target Species of Antibody: Mouse
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Distilled Water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized, PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze. Freezing R-Phycoerythrin conjugates will result in substantial loss of activity.
- 储存条件
- 4 °C
- 储存方法
- Store at 4°C, do not freeze. Freezing R-Phycoerythrin conjugates will result in substantial loss of activity.
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- 抗原
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- 别名
- ITGAM / CD11b (ITGAM 产品)
- 背景
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Name/Gene ID: ITGAM
Family: Integrin
Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain - 基因ID
- 3684
- 途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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