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CD11b 抗体 (PE)

ITGAM 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal PE
产品编号 ABIN576512
发货至: 中国
  • 抗原 See all CD11b (ITGAM) 抗体
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
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    大鼠
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    小鼠
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    单克隆
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    This CD11b antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Recognizes the rat equivalent of human CD11b, the receptor for the iC3b component of complement. The antigen is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35 % of alveolar macrophages. The antibody also labels dendritic cells, granulocytes and microglial cells in the brain. Clone MRC OX-42 has been reported as being suitable for use on paraffin-embedded material following PLP fixation (periodate-lysine-paraformaldehyde). Functionally, clone OX-42 inhibits complement mediated rosettes(1). XXX recommend the use of MCA275EL for use in functional studies.
    纯化方法
    Ion exchange chromatography
    免疫原
    Rat peritoneal macrophages.

    Type of Immunogen: Cells
    亚型
    IgG2a
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  • 应用备注
    Approved: Flo (1:1)

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    说明

    Target Species of Antibody: Rat

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Distilled Water.
    浓度
    Lot specific
    缓冲液
    Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    别名
    ITGAM / CD11b (ITGAM 产品)
    背景
    Name/Gene ID: ITGAM
    Family: Integrin

    Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
    基因ID
    3684
    UniProt
    P11215
    途径
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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