GAP43 抗体
Quick Overview for GAP43 抗体 (ABIN576411)
抗原
See all GAP43 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes a protein originally termed 2G13P which is localized to growth cones. Subsequent investigation has identified this protein to be 40S ribosomal protein SA, also known as 37 kD laminin receptor precursor or Laminin receptor 1. 40S ribosomal protein SA is a 296 amino acid ~37kD membrane, cytoplasmic and nuclear protein required for the assembly and/or stability of the 40S ribosomal subunit. In vertebrate evolution the molecule has acquired a secondary function as a laminin receptor. In growth cones expression is notable particularly in filopodia and lamellipodia in developing rat CNS and embryonic neurons in culture. 40S ribosomal protein SA interacts with the filamentous actin cytoskeleton and therefore may be involved in growth cone motility. Has been used for the detection of growth cones by immunohistochemistry and identification of 40S ribosomal protein SA by western blotting in chicken and rat samples.
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免疫原
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Embryonic chick tectal membranes.
Type of Immunogen: Membrane fraction -
亚型
- IgM
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应用备注
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Approved: Flo, IHC, IHC-Fr, IHC-P
Usage: Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. -
说明
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Target Species of Antibody: Chicken
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Tissue culture supernatant, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- GAP43 (Growth Associated Protein 43 (GAP43))
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别名
- GAP43
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背景
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Name/Gene ID: GAP43
Family: Neuromodulin
Synonyms: GAP43, Axonal membrane protein GAP-43, B-50, Growth associated protein 43, Growth-associated protein 43, Neural phosphoprotein B-50, Neuromodulin, PP46, GAP-43, Protein F1 -
基因ID
- 2596
抗原
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