CD13 抗体 (AA 288-295) (PE)
Quick Overview for CD13 抗体 (AA 288-295) (PE) (ABIN576340)
抗原
See all CD13 (ANPEP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 288-295
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特异性
- Recognizes human CD13 also known as aminopeptidase N. CD13 is a single pass type II glycosylated integral membrane protein with a predicted molecular mass of ~110 kD and an apparent molecular mass of ~150 kD expressed by granulocytes, monocytes, fibroblasts, endothelial cells and by myeloid leukaemia cells. CD13 acts as a major cell surface receptor for group 1 coronoviruses which bind to a critical sequence encompassing amino acid residues 288-295. CD13 functions as an enzyme, a metalloprotease present as both a membrane bound form and also a soluble aminopeptidase N. Inhibits infection of cells by human coronavirus but not hepatitis C virus and inhibits aminopeptidase N activity of the CD13 Molecule.
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纯化方法
- Protein A purified
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免疫原
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Human AML cells.
Type of Immunogen: Cells -
亚型
- IgG1
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应用备注
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Approved: ELISA, Flo (1:1), IHC, IHC-Fr, IP, WB
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Distilled Water.
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浓度
- Lot specific
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缓冲液
- Lyophilized, PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
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别名
- ANP / CD13
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背景
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Name/Gene ID: ANPEP
Subfamily: Metallopeptidase M1
Family: Exopeptidase
Synonyms: ANPEP, Alanyl aminopeptidase, Aminopeptidase M, APN, Aminopeptidase N, AP-N, AP-M, CD13, CD13 antigen, HAPN, gp150, p150, PEPN, Microsomal aminopeptidase, LAP1 -
基因ID
- 290
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途径
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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