Connexin 31 抗体 (pSer368)
Quick Overview for Connexin 31 抗体 (pSer368) (ABIN576289)
抗原
See all Connexin 31 (GJB3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer368
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特异性
- Recognizes the ~43 kD Connexin43, when phosphorylated at Ser368. Connexin43 (CX43) allows for the exchange of solutions between neighboring cells through the formation of gap-junctional channels and is expressed in the brain, kidneys and myocardium, as well as vascular endothelial cells. A decrease in the permeability of gap-junctional channels occurs due to a conformational change in the structure of CX43, and that this is mediated by the phosphorylation of CX43 at residue Ser368, by Protein Kinase C. A possible link between CX43 and epilepsy has been investigated following the detection of high levels of CX43 in both low-grade tumors and peritumoural reactive astrocytes.
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纯化方法
- Purified
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免疫原
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Synthetic phosphopeptide corresponding to an amino acid sequence within connexin43 which includes phosphorylated Ser368 ( pSer368 ).
Type of Immunogen: Synthetic phospho-peptide -
亚型
- IgG
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anti-Gap Junction Protein, beta 3, 31kDa (GJB3) (AA 1-270) antibody
GJB3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B4-1B3 unconjugated
anti-Gap Junction Protein, beta 3, 31kDa (GJB3) (AA 211-270) antibodyGJB3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 3, 31kDa (GJB3) (C-Term) antibodyGJB3 适用: 小鼠 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 3, 31kDa (GJB3) (C-Term) antibodyGJB3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 3, 31kDa (GJB3) (N-Term) antibodyGJB3 适用: 人, 小鼠, 大鼠, 犬, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 3, 31kDa (GJB3) (AA 7-102) antibodyGJB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 3, 31kDa (GJB3) (AA 211-269) antibodyGJB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 3, 31kDa (GJB3) (AA 213-270) antibodyGJB3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 3, 31kDa (GJB3) (AA 84-174) antibodyGJB3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 3, 31kDa (GJB3) (AA 210-270) antibodyGJB3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Approved: WB (1:1000)
Usage: Western Blot: LS-C43142 detects a band of approximately 43kD in rat hippocampus cell lysates. -
说明
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Target Species of Antibody: Rat
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 10 mM HEPES, pH 7.5, 0.09 % sodium azide, 0.01 % BSA, 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))
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别名
- GJB3 / CX31 / Connexin 31
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背景
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Name/Gene ID: GJB3
Subfamily: Connexin
Family: Ion Channel
Synonyms: GJB3, Connexin 31, Connexin-31, CX31, DFNA2, Erythrokeratodermia variabilis, Gap junction beta-3 protein, DFNA2B, EKV, Gap junction protein beta 3 -
基因ID
- 2707
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途径
- Sensory Perception of Sound
抗原
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