Tyrosine Hydroxylase 抗体
Quick Overview for Tyrosine Hydroxylase 抗体 (ABIN576288)
抗原
See all Tyrosine Hydroxylase (TH) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes tyrosine hydroxylase (TH). Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.
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纯化方法
- Purified
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免疫原
- Tyrosine hydroxylase purified from pheochromocytoma.
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亚型
- IgG
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应用备注
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Approved: IF (1:1000), IHC, IHC-Fr (1:1000), WB (1:1000)
Usage: Western Blot: LS-C43105 detects a band of approximately 60kD in rat caudate cell lysates. -
说明
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Target Species of Antibody: Rat
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 10 mM HEPES, pH 7.5, 0.09 % sodium azide, 0.01 % BSA, 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Tyrosine Hydroxylase (TH)
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别名
- TH / Tyrosine Hydroxylase
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背景
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Name/Gene ID: TH
Family: Monooxygenase
Synonyms: TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase -
基因ID
- 7054
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途径
- Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
抗原
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