NG2 抗体 (Extracellular Domain)
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Quick Overview for NG2 抗体 (Extracellular Domain) (ABIN7699076)
抗原
See all NG2 (MCSP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Extracellular Domain
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原理
- Rabbit antibody to NG2
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特异性
- Specific for NG2.
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交叉反应
- 小鼠
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from extracellular domain of mouse NG2 conjugated to blue carrier protein was used as the antigen.
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亚型
- IgG
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anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 2247-2308) antibody
MCSP 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7G4E5 unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 1919-2258) antibodyMCSP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 1950-2210) antibodyMCSP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 559-776) antibodyMCSP 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 6# unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 2247-2308) antibodyMCSP 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) (AA 1950-2210) antibodyMCSP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyMicroarray verified MCSP 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB300756 unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyMicroarray verified MCSP 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB41136 unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyMCSP 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) antibodyKD Validated MCSP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3470 unconjugated Recombinant Antibody
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应用备注
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
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别名
- NG2
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背景
- Valuable marker for several incompletely differentiated precursor cells. Function: Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4 beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42 ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades. Subcellular location: Apical cell membrane, Single-pass type I membrane protein, Extracellular side. Cell projection ‰ lamellipodium membrane, Single-pass type I membrane protein, Extracellular side. Tissue specificity: Expressed in microcascular pericytes and not endothelial cells.
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UniProt
- Q8VHY0
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途径
- Glycosaminoglycan Metabolic Process
抗原
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