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IL2RG 抗体 (PE)

This anti-IL2RG antibody (ABIN5710229) is a Rat Monoclonal antibody detecting IL2RG in FACS. Suitable for Human, Dog.
产品编号 ABIN5710229
发货至: 中国

Quick Overview for IL2RG 抗体 (PE) (ABIN5710229)

抗原

See all IL2RG 抗体
IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

适用

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人, 犬

宿主

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大鼠

克隆类型

  • 65
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单克隆

标记

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This IL2RG antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

TUGh4
  • 原理

    Anti-Hu CD132 PE

    特异性

    The rat monoclonal antibody TUGh4 recognizes an extracellular epitope of CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes.

    交叉反应 (详细)

    Human, Canine (Dog)

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Human CD132-transfected cell line

    亚型

    IgG2b kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

    别名

    CD132

    背景

    Interleukin 2 receptor subunit gamma,CD132 / common gamma chain is an essential component of receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21, and it is critical for development of the immune system. Its mutation causes X-linked severe combined immunodeficiency disease (XSCID). CD132 is expressed on lymphocytes, NK cells, monocytes, and granulocytes. Through its cytoplasmic part which containsfour tyrosines and an SH2 domain, CD132 transcuces signal to downstream JAK/STAT pathway.,common gamma chain, IL2RG, SCIDX, IMD4

    基因ID

    3561

    UniProt

    P31785

    途径

    JAK/STAT Signaling, Growth Factor Binding
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