UGT1A1 抗体
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Quick Overview for UGT1A1 抗体 (ABIN5708492)
抗原
See all UGT1A1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity purified
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免疫原
- A recombinant human partial protein corresponding to amino acids E316-H533 was used as the immunogen for the UGT1A1 antibody.
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亚型
- IgG
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anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 1-200) antibody
UGT1A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) antibodyUGT1A1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 316-533) antibodyUGT1A1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 395-482) antibodyUGT1A1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 54-159) antibodyUGT1A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 65-90), (N-Term) antibodyUGT1A1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB22607 unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 251-300) antibodyUGT1A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) (AA 36-85) antibodyUGT1A1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the UGT1A1 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the UGT1A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
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别名
- UGT1A1
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背景
- UDP-glucuronosyltransferase 1-1 also known as UGT-1A is an enzyme that in humans is encoded by the UGT1A1 gene. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.
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UniProt
- P22309
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途径
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
抗原
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