ABCC8 抗体
Quick Overview for ABCC8 抗体 (ABIN5708360)
抗原
See all ABCC8 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids TIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVTERKA from the human protein were used as the immunogen for the SUR1 antibody.
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亚型
- IgG
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anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 679-929) antibody
ABCC8 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibodyABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (HRP)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 HRP
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (FITC)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 FITC
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (Biotin)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 Biotin
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (PE)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 PE
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (PerCP)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 PerCP
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (APC)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 APC
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (Atto 488)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 Atto 488
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 1548-1582) antibody (Atto 594)ABCC8 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S289-16 Atto 594
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应用备注
- Optimal dilution of the SUR1 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the SUR1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))
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别名
- ABCC8 / SUR1
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背景
- ATP-binding cassette transporter sub-family C member 8 is a protein that in humans is encoded by the ABCC8 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene.
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UniProt
- Q09428
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途径
- Negative Regulation of Hormone Secretion
抗原
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