CNR1 抗体
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北京 101111
Quick Overview for CNR1 抗体 (ABIN5708215)
抗原
See all CNR1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity purified
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免疫原
- A recombinant human protein corresponding to amino acids M1-Q75 was used as the immunogen for the CB1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CB1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, IHC (FFPE): 01-2 μg/mL,FACS: 1-3 μg/10^6 cells, Direct ELISA: 0.1-0.5 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the CB1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- CNR1 (Cannabinoid Receptor 1 (CNR1))
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别名
- CB1
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背景
- The cannabinoid receptor type 1, often abbreviated as CB1, is a G protein-coupled cannabinoid receptor located primarily in the central and peripheral nervous system. This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
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UniProt
- P21554
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途径
- Feeding Behaviour
抗原
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