NAT10
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
Alexa Fluor 750
应用备注
The stated application concentrations are suggested starting points. Titration of the NAT10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000
限制
仅限研究用
缓冲液
In 1X PBS, pH 7.4, with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the NAT10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
NAT10 has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.